美國緝毒局探員和臥底海軍情報員分別被下令調查對方底細，兩人後來發現彼此都落入犯罪集團的圈套裡......。

Academy Award® winner Denzel Washington and Mark Wahlberg lead an all-star cast in 2 Guns, an explosive action film that tracks two operatives from competing bureaus who are forced on the run together. But there is a big problem with their unique alliance: Neither knows that the other is an undercover federal agent.

For the past 12 months, DEA agent Bobby Trench (Washington) and U.S. naval intelligence officer Marcus Stigman (Wahlberg) have been reluctantly attached at the hip. Working undercover as members of a narcotics syndicate, each man distrusts his partner as much as the criminals they have both been tasked to take down.

When their attempt to infiltrate a Mexican drug cartel and recover millions goes haywire, Trench and Stigman are suddenly disavowed by their superiors. Now that everyone wants them in jail or in the ground, the only person they can count on is the other. Unfortunately for their pursuers, when good guys spend years pretending to be bad, they pick up a few tricks along the way.